ABSTRACT
The antibacterial activity of three type of medicate soap on staphylococcus aureus isolated from wound infections was conducted. Fifty individual with would infection within the age range of 9-73 years were sampled. Swabsticks were used to collect specimens from wound infection. each swabstick was streaked separately over plates of nutrient and macconkey agar and later incubated at 370c. out of the fifty (50) individuals sampled 25(50%) were mostly infected with staphylococcus aureus followed by pseudomonas acruginqu (22%) staphylococcus epidermis (10%) least by Exchericha coli b(12%) The organisms occur within the age range 9-13 years with 8 (16%) followed by 14-18 years 4(8%) next by the age range of 19-23 years 3(6%) followed by 24-28 years with 2(4%) followed 24-28 years with 2(4%) and the heart in the age range are 29-33,34-38,39-43,44-48,49-53,54-58 64-68 with 1(2%) each while there was no isolation in the age range 59-63. The study also revealed that all the staphylococcus aureus isolated were sensitive to the three medicated soap. The means of inhibition was highest in Aleppo medicated soap with 12.92 mm followed by temperate medicated soap with 11.2mm and least in carat medicated soap with 10.56 mm. Also the staphylococcus aureus isolated were also sensitive to the commercial autibutics used as couplers the means zones of inhibition was highest in ampiclox with 12.8 mm followed by gentamyain with 12.04 mm and the heart in penicillin with 10.4 mm. there was a close relationship in the zenes of inhibition between the three medicated soap and the commercial antibiotics used as coconutrels. The result showned that medicated soaps were effective against staphylococcus aureus involved in would infection in humans and are comparable to commercial antibiotics. There fore medicated soap can be used in cleaning the skin particularly in the affected part of the skin during the time one has hurt or cut on the skin.
TABLE OF CONTENTS
Title page
Certification
Dedication
Acknowledgement
Abstract
Table of contents
List of table
CHAPTER ONE
1.0Introduction
1.1Aims and objectives
1.2Statement of the problem
1.3Hypothesis
1.4Justification of the study
1.5Limitation Of The Study
CHAPTER TWO
2.0Literature review
2.1Antibacterial activity of soap
2.2Medical relevance of antimicrobial soap
2.3Normal skin microbiota and soap
CHAPTER THREE
3.0Material and methods
3.1Materials
3.2 sterilization
3.2.2Collection of soap sample
3.2.3Preparation of culture media
3.2.4Collection of bacterial organisms from would infection
3.2.5Microbial count, grams stain and microscopic examination
3.2.6Biochemical test for identification of isolates
CHAPTER FOUR
Result
CHAPTER FIVE
Discussion
CHAPTER SIX
Conclusion and recommendation
References
Appendix
