The purpose of this study was to investigate the reasons for poor enrollment of girls in Isiolo sub county with focus on, how security and safety influence their enrollment in schools: assessing the type of curriculum adopted in schools and how it affected female enrolment; identify traditional practices which influence girl child enrollment in schools and assessing the relationship between gender preference and girl child enrolment. The population used included 36 teachers from Isiolo Sub County. A questionnaire was structured to collected relevant data. Findings indicated that government had not adequately formulated policies to safe guard girl children’s rights both within and outside school. It was because of this that many girls were missing in schools because they were not protected at all. It was also established that the curriculum materials were not favorable and therefore gender biased towards the girls. This was a discouraging factor for girls to enroll in schools. They were some harmful traditional practices which were keeping girls away from schools and in particular female gentile mutilation. Findings also indicated that the parents had a negative attitude towards girl children education and therefore they were not giving them a chance to participate fully in class activities. It was recommended that legal action should be taken on those parents who were refusing their girl children to enroll in schools; that religious leaders help in sensitizing the public about undesirable cultural practices and that successful females act as role models to the young ones to emulate; to carry out civic education about the value of girl children education.